Concise synthesis and characterization of unsymmetric 1,3-benzoxazines by tandem reactions
β Scribed by Imran, Muhammad; Kiskan, Baris; Yagci, Yusuf
- Book ID
- 120619345
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 891 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The present review covers the synthesis and reactions of 2βheteroβ4__H__β3,1βbenzoxazinβ4βones which include oxygen, sulfur and nitrogen substituents. Literature coverage includes publications primarily from the mid 1960's to December 1999.
A convenient, efficient method for the preparation of benzoxazines is described. 2-(Hydroxyiminomethyl)benzyl alcohols were cyclodehydrated to construct 1H-2,3-benzoxazines by acid-catalyzed intramolecular Mitsunobu reaction. This reaction depended on the geometry of the hydroxyimino moiety in the r