Concise syntheses of racemic and enantio
โ
Bao Khanh Le Nguyen; Nicole Langlois
๐
Article
๐
2003
๐
Elsevier Science
๐
French
โ 100 KB
Racemic deoxydysibetaine was efficiently obtained in few steps from methyl pyroglutamate. The 2S enantiomer was synthesized from (S)-pyroglutaminol as chiral starting material, through the key intermediate (S)-2-hydroxymethylglutamic acid recently prepared with complete stereoselectivity in our labo