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Concise copper-catalyzed one-pot tandem synthesis of benzimidazo[1,2-b]isoquinolin-11-one derivatives

✍ Scribed by Lu, Juyou; Gong, Xiaoyu; Yang, Haijun; Fu, Hua


Book ID
119968377
Publisher
Royal Society of Chemistry
Year
2010
Tongue
English
Weight
577 KB
Volume
46
Category
Article
ISSN
1359-7345

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One-pot concise syntheses of benzimidazo
✍ Noriko Okamoto; Keisuke Sakurai; Minoru Ishikura; Kei Takeda; Reiko Yanada πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 French βš– 514 KB

Direct, efficient syntheses of the benzimidazo[2,1-a]isoquinoline ring system have been achieved with 2bromoarylaldehydes, terminal alkynes, and 1,2-phenylenediamines by a microwave-accelerated tandem process in which a Sonogashira coupling, 5-endo cyclization, oxidative aromatization, and 6-endo cy