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Concentrations of three hapten-binding immunoglobulins in pooled normal human serum

✍ Scribed by K. Karjalaninen; O. Mäkelä


Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
677 KB
Volume
6
Category
Article
ISSN
0014-2980

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✦ Synopsis


Abstract

The amount of natural anti‐DNP‐cap, anti‐NIP‐cap or anti‐ABA‐TYR in human IgM was measured by using immunoabsorbents and hapten elution. We found that 1.0 % of pooled human IgM is specific for DNP‐cap, 0.2 % for NIP‐cap and 0.02 % for ABA‐TYR. Haptens NIP and DNP were found to be cross‐reactive when tested with natural antibodies even though they were not cross‐reactive when tested with immune antibodies.


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