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Concentrating missense mutations in core gene of hepatitis B virus

โœ Scribed by Wan-Long Chuang; Masao Omata; Toshiki Ehata; Osamu Yokosuka; Masao Ohto


Book ID
112515333
Publisher
Springer US
Year
1993
Tongue
English
Weight
609 KB
Volume
38
Category
Article
ISSN
0163-2116

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The core promoter region of hepatitis B virus genomes regulates transcription of the precore and pregenomic mRNAs encoding hepatitis B e antigen (HBeAg) and core antigen that contain target epitopes for cytotoxic T lymphocytes. The prevalence and clinical significance of mutations in this region wer