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Comutagenicity, competitive enzyme substrates, and in vitro carcinogenicity assays

โœ Scribed by John Ashby; J.A. Styles


Book ID
113249236
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
469 KB
Volume
54
Category
Article
ISSN
0165-1161

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In vitro sister chromatid exchange (SCE) and chromosome aberration (ABS) tests have been extensively used to identify potential rodent carcinogens. A number of measures of potency were developed to describe in vitro SCE and ABS test results: the dose needed to induce a unit increase over the control