Intercalative binding of the antitumor drugs amonafide and azonafide to the oligonucleotide duplex d(GGCCGGCCGG).d(CCGGCCGGCC) was compared using molecular dynamics in vacuum with the AMBER force field. A number of reasonable possible binding conformations were obtained, with the azonafide complexes
Computer simulation study of the binding of an antiviral agent to a sensitive and a resistant human rhinovirus
β Scribed by Terry P. Lybrand; J. Andrew McCammon
- Publisher
- Springer Netherlands
- Year
- 1989
- Tongue
- English
- Weight
- 381 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0920-654X
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