Computer simulation of the binding of am
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Soaring Bear; William A. Remers
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Article
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1996
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Springer Netherlands
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English
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Intercalative binding of the antitumor drugs amonafide and azonafide to the oligonucleotide duplex d(GGCCGGCCGG).d(CCGGCCGGCC) was compared using molecular dynamics in vacuum with the AMBER force field. A number of reasonable possible binding conformations were obtained, with the azonafide complexes