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Computer Simulation of Protein-induced Structural Changes in Closed Circular DNA

✍ Scribed by Peisen Zhang; Irwin Tobias; Wilma K. Olson


Book ID
115627099
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
35 KB
Volume
251
Category
Article
ISSN
0022-2836

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## Abstract The prediction of changes in protein stability and structure resulting from single amino acid substitutions is both a fundamental test of macromolecular modeling methodology and an important current problem as high throughput sequencing reveals sequence polymorphisms at an increasing ra