𝔖 Bobbio Scriptorium
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Computer predicts cytochrome P450-dependent drug interactions

Book ID
120872053
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
1999
Weight
194 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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✍ C. L. DeVane πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 123 KB

The magnitude of drugΒ±drug interactions in vitro involving competitive inhibition of cytochrome (CYP) isozymes by newer antidepressants can theoretically be shown to be dependent upon several factors. These include the concentration of both the substrate and inhibitor, the anity of the inhibitor for