✦ LIBER ✦

Computer aided experimentation in countercurrent reaction chromatography and simulated countercurrent chromatography

✍ Scribed by Barry B. Fish; Robert W. Carr; Rutherford Aris

Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 725 KB
Volume: 43
Category: Article
ISSN: 0009-2509
DOI: 10.1016/0009-2509(88)87055-6

No coin nor oath required. For personal study only.

✦ Synopsis

A continuous countercurrent moving bed chromatographic reactor, and a simulated countercurrent moving bed apparatus have been interfaced with a laboratory microcomputer for data acquisition and computer control. Simulation of a countercurrent moving bed is accomplished by switching a feedstream sequentially through a series of columns. Continuous motion of the bed past the feed, which characterizes true counter-currency, is replaced by discretiaed motion of the feed past the bed. Experimental characterization of the detailed behavior of these configurations requires many analyses of product streams to be done rapidly, virtually mandating computerization. Interfacing of the apparatus with an IB?I PC-XT is described. Representative experimental data from both types of apparatus are presented and briefly discussed.

📜 SIMILAR VOLUMES

The rôle of countercurrent chromatograph

The rôle of countercurrent chromatography in the fractionation of complex mixtures

✍ Al-Shammary, Fahad Jaber ;Mian, Neelofur Abdul Aziz ;Mian, Mohammad Saleem 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 1005 KB

## Abstract The biologically active pricipals in nature are frequently present as only a few parts per million of complex mixtures of non‐volatile components and often have limited stability. Their isolation often requires the application of all available techniques, such as adsorption chromatograp

Modeling the performance of pilot-scale

Modeling the performance of pilot-scale countercurrent chromatography: Scale-up predictions and experimental verification of erythromycin separation

✍ A.J. Booth; I. A. Sutherland; G. J. Lye 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 1 views

Experimental and theoretical studies of

Experimental and theoretical studies of countercurrent solvent-gas extraction—I Continuous gas-chromatography in a laboratory moving-bed column

✍ D.W. Pritchard; M.E. Probert; P.F. Tiley 📂 Article 📅 1971 🏛 Elsevier Science 🌐 English ⚖ 631 KB

The experimental results of separation of binary volatile mixtures in a 25 mm column have been compared with the results of a multi-stage computation procedure based on established phaseequilibrium data. Very approximate agreement between experiment and theory is obtained assuming an HETP of 13-18 m

Enantiomer separation of 7-des-methyl-or

Enantiomer separation of 7-des-methyl-ormeloxifene using sulfated β-cyclodextrin in countercurrent chromatography

✍ Jens Breinholt; Søren Vig Lehmann; Annemarie Reinhardt Varming 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB 👁 1 views

The enantiomers of 7-des-methyl-ormeloxifene were separated by countercurrent chromatography (CCC) using sulfated ␤-cyclodextrin as chiral selector, representing the first reported successful application of a cyclodextrin derivative in CCCbased resolutions. The choice of chiral selector relies on ex

Using countercurrent chromatography to a

Using countercurrent chromatography to assist in the purification of new Annonaceous acetogenins from Annona squamosa

✍ D. Craig Hopp; Walter D. Conway; Jerry L. McLaughlin 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB 👁 2 views

Three new Annonaceous acetogenins, (2,4-cis and trans)-9-hydroxy asimicinone (1), (2,4-cis and trans)squamoxinone B (2) and (2,4-cis and trans) squamoxinone C (3), were isolated from the bark of Annona squamosa with the help of countercurrent chromatography. Additionally found was isoannoreticuin (4

Enzymatic transformation of platycosides

Enzymatic transformation of platycosides and one-step separation of platycodin D by high-speed countercurrent chromatography

✍ In Jin Ha; Young Wan Ha; Minseok Kang; Jongsung Lee; Deokhoon Park; Yeong Shik K 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB

## Abstract Platycosides, the saponins found in the roots of __Platycodon grandiflorum__ (Platycodi Radix), are typically composed of oleanane triterpenes with two side chains. In platycosides, platycodin D, a glucose unit at C‐3, is a major component, which has several pharmacological activities.