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Computational Simulations of Interactions of Scorpion Toxins with the Voltage-Gated Potassium Ion Channel

โœ Scribed by Yu, Kunqian; Fu, Wei; Liu, Hong; Luo, Xiaomin; Chen, Kai Xian; Ding, Jianping; Shen, Jianhua; Jiang, Hualiang


Book ID
119988838
Publisher
Biophysical Society
Year
2004
Tongue
English
Weight
1007 KB
Volume
86
Category
Article
ISSN
0006-3495

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Solution structure of maurotoxin, a scor
โœ E. Blanc; J.M. Sabatier; R. Kharrat; S. Meunier; M. El Ayeb; J. Van Rietschoten; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 488 KB ๐Ÿ‘ 2 views

Maurotoxin (MTX), purified from the scorpionid Scorpio maurus is a potent ligand for potassium channels. It shows a broad specificity as being active on Kv1.1 (Kd โ€ซุโ€ฌ 37 nM), Kv1.2 (Kd โ€ซุโ€ฌ 0.8 nM), Kv1.3 (Kd โ€ซุโ€ฌ 150 nM) voltage-gated potassium channels, as well as on small-conductance calcium-activa