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Brownian Dynamics Simulations of Interaction Between Scorpion Toxin Lq2 and Potassium Ion Channel

โœ Scribed by Cui, Meng; Shen, Jianhua; Briggs, James M.; Luo, Xiaomin; Tan, Xiaojian; Jiang, Hualiang; Chen, Kaixian; Ji, Ruyun


Book ID
118514442
Publisher
Biophysical Society
Year
2001
Tongue
English
Weight
791 KB
Volume
80
Category
Article
ISSN
0006-3495

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โœ Jean-Guillaume Renisio; Zhe Lu; Eric Blanc; Weili Jin; John H. Lewis; Olivier Bo ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 653 KB

Lq2 is a unique scorpion toxin. Acting from the extracellular side, Lq2 blocks the ion conduction pore in not only the voltage-and Ca 2ุ‰ -activated channels, but also the inward-rectifier K ุ‰ channels. This finding argues that the threedimensional structures of the pores in these K ุ‰ channels are si