The energetics of substrate dephosphorylation in the low-molecularweight protein tyrosine phosphatase is studied with the empirical valence bond method in combination with molecular dynamics free energy perturbation simulations. Different mechanisms corresponding to different charge states of the re
Computational modeling of the rate limiting step in low molecular weight protein tyrosine phosphatase
✍ Scribed by Karin Kolmodin; Johan Åqvist
- Book ID
- 117111240
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 139 KB
- Volume
- 456
- Category
- Article
- ISSN
- 0014-5793
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