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Computational Methods for Genetics of Complex Traits

✍ Scribed by Jay C. Dunlap and Jason H. Moore (Eds.)


Publisher
Academic Press
Year
2010
Tongue
English
Leaves
211
Series
Advances in Genetics 72
Edition
1
Category
Library

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✦ Synopsis


The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics reasearch. This thematic volume of Advances in Genetics looks at Computational Methods for Genetics of Complex traits. The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics reasearch. This thematic volume of Advances in Genetics looks at Computational Methods for Genetics of Complex traits.

✦ Table of Contents


Content:
Series Editors
Page ii

Copyright
Page iv

Contributors
Pages ix-x

1 - Genome Simulation: Approaches for Synthesizing In Silico Datasets for Human Genomics
Pages 1-24
Marylyn D. Ritchie, William S. Bush

2 - Logic Regression and Its Extensions
Pages 25-45
Holger Schwender, Ingo Ruczinski

3 - Complex System Approaches to Genetic Analysis: Bayesian Approaches
Pages 47-71
Melanie A. Wilson, James W. Baurley, Duncan C. Thomas, David V. Conti

4 - Multigenic Modeling of Complex Disease by Random Forests
Pages 73-99
Yan V. Sun

Chapter 5 - Detecting, Characterizing, and Interpreting Nonlinear Gene–Gene Interactions Using Multifactor Dimensionality Reduction
Pages 101-116
Jason H. Moore

6 - The Restricted Partition Method
Pages 117-139
Robert Culverhouse

7 - Statistical Methods for Pathway Analysis of Genome-Wide Data for Association with Complex Genetic Traits
Pages 141-179
Peter Holmans

8 - Providing Context and Interpretability to Genetic Association Analysis Results Using the KGraph
Pages 181-193
Reagan J. Kelly, Jennifer A. Smith, Sharon L.R. Kardia

Subject Index
Pages 195-200


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