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Comprehensive Structural Studies of 2′,3′-Difluorinated Nucleosides: Comparison of Theory, Solution, and Solid State

✍ Scribed by Barchi, Joseph J.; Karki, Rajeshri G.; Nicklaus, Marc C.; Siddiqui, Maqbool A.; George, Clifford; Mikhailopulo, Igor A.; Marquez, Victor E.


Book ID
126980785
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
773 KB
Volume
130
Category
Article
ISSN
0002-7863

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The new N-salicylideneheteroarenamines 1 -4 were prepared by reacting the biologically relevant 3hydroxy-4-pyridinecarboxaldehyde (5) with 1H-imidazol-1-amine (6), 1H-pyrazol-1-amine ( 7), 1H-1,2,4triazol-1-amine ( 8), and 1H-1,3,4-triazol-1-amine (9). Solution 1 H-, 13 C-, and 15 N-NMR were used to