𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance

✍ Scribed by Carl J. Baldick; Daniel J. Tenney; Charles E. Mazzucco; Betsy J. Eggers; Ronald E. Rose; Kevin A. Pokornowski; Cheng F. Yu; Richard J. Colonno


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
401 KB
Volume
47
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


In vitro evaluation of hepatitis B virus
✍ Xiaofeng Xiong; Huiling Yang; Christopher E. Westland; Ruiming Zou; Craig S. Gib πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 134 KB πŸ‘ 1 views

Several mutations (V521L, P525L, L528M, T532S, and V555I) in the gene for hepatitis B virus (HBV) polymerase have been identified in HBV isolated from patients that displayed break-through viremia during famciclovir treatment. To determine whether these mutations cause phenotypic resistance to famci

Antiviral efficacy of combination therap
✍ Hyo-Joon Yang; Jeong-Hoon Lee; Yoon Jun Kim; Jung-Hwan Yoon; Hyo-Suk Lee πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 172 KB

## Abstract There is little clinical information on the management of hepatitis B virus (HBV) that is resistant to multiple drugs including entecavir (ETV). The present retrospective cohort study assessed the antiviral efficacy of ETV/adefovir dipivoxil (ADV) combination therapy for ETV‐resistant H

Characteristics of lamivudine-resistant
✍ Norio Horiike; Tran Nhu Duong; Kojiro Michitaka; Kouji Joko; Yoichi Hiasa; Ichir πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 207 KB πŸ‘ 2 views

## Abstract Lamivudine therapy often causes breakthrough of hepatitis B virus (HBV) DNA and breakthrough hepatitis. The aim of this study was to determine the viral factors that relate to HBV‐DNA breakthrough with and without breakthrough hepatitis. Among 82 patients with chronic hepatitis B (CHB)

Novel patterns of amino acid mutations i
✍ Ogata, Norio; Fujii, Kyuichi; Takigawa, Shingo; Nomoto, Minoru; Ichida, Takafumi πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 160 KB πŸ‘ 2 views

Lamivudine is effective in suppressing replication of hepatitis B virus (HBV). However, the emergence of HBV variants resistant to lamivudine is a concern. Lamivudine resistance has been attributed mainly to a substitution of isoleucine or valine for methionine at residue 550 (M550I or M550V) in the

Frequent detection of hepatitis B virus
✍ S. Gloria Selabe; Ernest Song; Rosemary J. Burnett; M. Jeffrey Mphahlele πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 83 KB πŸ‘ 2 views

## Abstract This retrospective study investigated and characterized the YMDD motif of the hepatitis B virus (HBV) reverse transcriptase (RT) gene, in sequential samples of 17 South African patients with chronic hepatitis B infection on lamivudine treatment. The profile of HBV genotypes as well as t

Prediction of sustained virological resp
✍ Guy W. Neff; Christopher B. O'Brien; Robert Cirocco; Marzia Montalbano; Maria de πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 69 KB πŸ‘ 2 views

The optimal duration of therapy for pegylated interferon combined with ribavirin in recurrent Hepatitis C virus (HCV) following liver transplantation is not known. We wanted to determine if testing for HCV in liver tissue by reverse transcriptase polymerase chain reaction (RT-PCR) was superior in pr