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Comprehensive Chirality || 6.20 C–X Bond Formation: α-Halogenation of Carbonyl Compounds

✍ Scribed by Kano, T.


Book ID
118028567
Publisher
Elsevier
Year
2012
Weight
30 KB
Category
Article
ISBN
0080951686

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Completely stereoselective PC bond form
✍ Tin-Lok Au-Yeung; Ka-Yee Chan; Richard K Haynes; Ian D Williams; Lam Lung Yeung 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 114 KB

Upon treatment with LDA or alkyllithium, enantiomers of P-chiral phosphinates, phosphinothioates, phosphinoamidates, thionophosphinates, thionophosphinothioates and thionophosphinoamidates undergo clean [1,3]-and [1,2]-rearrangements with complete stereoselectivity, with retention of configuration a