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Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase

โœ Scribed by Oscar M Aparicio; Deborah M Weinstein; Stephen P Bell


Book ID
117269005
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
621 KB
Volume
91
Category
Article
ISSN
0092-8674

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## Abstract **Background:** MCM and Cdc45 are required for the initiation and elongation stages of eukaryotic DNA replication. Recent studies show that a purified Mcm4/6/7 complex has DNA helicase activity. However, the biochemical function of the MCM complex and Cdc45 bound to chromatin has not be