Inclusion complexation of doxorubicin an
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O. Bekers; J.H. Beijnen; M. Otagiri; A. Bult; W.J.M. Underberg
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Article
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1990
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Elsevier Science
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English
⚖ 225 KB
The interaction of alpha-, beta- and gamma-cyclodextrins with the anthracycline antibiotics doxorubicin and daunorubicin was investigated by LC, circular dichroism (CD) and absorption spectroscopy. All studies were performed in aqueous media at different temperatures and pH values. The anthracycline