Antitumor cell and antimetabolic effects
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Jan Balzarini; Erik Clercq; Gebhard Kiefer; Klaus Keppeler; Alfred Buchele
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Article
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1984
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Springer US
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English
⚖ 764 KB
A series of forty 5'-ester derivatives of 5-ethyl-2'-deoxyuridine (EDU) have been evaluated for their inhibitory effects on the growth and metabolism of routine leukemia L1210 cells. Several EDU esters proved as potent as EDU in their inhibitory effects on L1210 cell growth (inhibitory dose-50: 5-10