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Complete reversal of enantioselection using oxazoline-containing Schiff base ligands derived from l-serine in enantioselective addition of diketene to aldehydes

โœ Scribed by Changhu Chu; Koji Morishita; Takanori Tanaka; Masahiko Hayashi


Book ID
108284141
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
171 KB
Volume
17
Category
Article
ISSN
0957-4166

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Synthesis of chiral ligands derived from
โœ Jun Lu; Xuenong Xu; Cunde Wang; Jiangang He; Yuefei Hu; Hongwen Hu ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 131 KB

A novel procedure for selective direct N,N-alkylation of the chiral Betti base was developed, and a new family of chiral ligands, (S)-1-(a-cycloaminobenzyl)-2-naphthols, were prepared. The ligands with five-and six-membered cyclic amines showed highly efficient asymmetric induction in the addition o