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Complete inhibition of poly(ADP-ribose) polymerase activity prevents the recovery of C3H1OT1/2 cells from oxidative stress

✍ Scribed by Girish M. Shah; Daniele Poirier; Serge Desnoyers; Sylvie Saint-Martin; Jean-Christophe Hoflack; Peimin Rong; Michele ApSimon; James B. Kirkland; Guy G. Poirier

Book ID
116106416
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
804 KB
Volume
1312
Category
Article
ISSN
0167-4889

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## Abstract Among different features of cancer cells, two of them have retained our interest: their nearly universal glycolytic phenotype and their sensitivity towards an oxidative stress. Therefore, we took advantage of these features to develop an experimental approach by selectively exposing can