Effects of a poly(ADP-ribose) polymerase inhibitor on mutation frequencies in dividing and quiescent C3H10T1/2 cells
β Scribed by Viyada Nunbhakdi; Elaine L. Jacobson
- Book ID
- 113193284
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 551 KB
- Volume
- 180
- Category
- Article
- ISSN
- 0027-5107
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We report on the individual and combined effects of doxorubicin (DOX) and hyperthermia (HYP) on nucleoid sedimentation and poly (ADP-ribose) polymerase (PARP) activity of L1210 cells. The effects of HYP and DOX on nucleoid sedimentation (increased sedimentation) were similar and correlated with cell