Complete association of loss of heterozygosity of chromosomes 13 and 17 in osteosarcoma
β Scribed by H. Scheffer; Y.C.M. Kruize; J. Osinga; G. Kuiken; J.W. Oosterhuis; J.A. Leeuw; H. Schraffordt Koops; C.H.C.M. Buys
- Book ID
- 119104896
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 683 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0165-4608
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Loss of heterozygosity (LOH) on chromosome I 3 and the age of patients at operation were studied in 46 cases of retinoblastoma (RB) tumors, of which 25 were hereditary and 21 were non-hereditary. The frequency of LOH was 70% for all informative tumors, but significantly higher in non-hereditary tumo