𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Complete assignments of the 1H and 13C resonances of 40-epi-(N1-tetrazolyl)-rapamycin and revised 13C assignments for rapamycin

✍ Scribed by Thomas G. Pagano

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
73 KB
Volume
43
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

Complete 1H and 13C assignments of 40-epi-(N1-tetrazolyl)-rapamycin (ABT-578) in DMSO-d6 were made using 1H, 13C, DQCOSY, ROESY, TOCSY, HSQC and HMBC spectra. Comparing the assignments with those of rapamycin showed that in the published 13C assignments of rapamycin in DMSO-d6 the shifts for C-12 and C-42 have been interchanged, as well as the shifts for C-1 and C-8.

📜 SIMILAR VOLUMES

Complete 1H and 13C NMR assignments of d
Complete 1H and 13C NMR assignments of diosgenyl saponins
✍ X. W. Han; H. Yu; X. M. Liu; X. Bao; B. Yu; C. Li; Y. Z. Hui 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 96 KB 👁 3 views

The complete assignments of 1H and 13C NMR data for a series of synthesized diosgenyl saponin analogs are described, viz. diosgenyl b-D-glucopyranoside (1), diosgenyl a-L-rhamnopyranosyl- 7). The assignments were achieved using homo-and heteronuclear two-dimensional NMR techniques.

Complete 1H and 13C NMR assignments of s
Complete 1H and 13C NMR assignments of stephalic acid
✍ Eleuterio Burgueño-Tapia; Luis R. Hernández; Pedro Joseph-Nathan; Manuel Salmón 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 41 KB 👁 2 views

In addition to 1D NMR methods and 2D shift-correlated NMR techniques (COSY and HETCOR), spin-spin simulation and MMX calculations, to obtain the minimum energy conformation structure, were used for the complete 1 H and 13 C NMR assignments of stephalic acid.

Complete 1H and 13C assignments of some
Complete 1H and 13C assignments of some epipodophyllotoxin derivatives
✍ Zaesung No; Sueg-Geun Lee 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 96 KB

## Abstract The complete analyses of the ^1^H and ^13^C NMR spectra of the __ortho__ ester analogues of etoposide are reported and differentiation of the α and β isomers of these derivatives is suggested by using the γ‐__gauche__ effect upon the ^13^C chemical shift. Copyright © 2003 John Wiley & S

Complete 1H and 13C assignments of fluor
Complete 1H and 13C assignments of fluorinated analogs of dehydroepiandrosterone
✍ Jason P. Burgess; James S. Wintermute; Brian F. Thomas; Izet M. Kapetanovic 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 91 KB

## Abstract The complete assignments of all ^1^H and ^13^C chemical shifts were made for the fluorinated dehydroepiandrosterone (DHEA) analog fluasterone, 2, and two potential __in vivo__ metabolites 3 and 4. The assignments were made using a combination of one‐ and two‐dimensional NMR techniques (

Complete 13C and 1H spectral assignments
Complete 13C and 1H spectral assignments of certain substituted quinoxalinones
✍ Valérie Rampont-Placidi; Benoit Cossec; Marie-Thérèse Brondeau; Pierre Mutzenhar 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB 👁 1 views

Two tagging reagents using a quinoxalinone Ñuorophore were synthesized and, for the Ðrst time, completely physicochemically characterized. The 1H and 13C spectra were entirely assigned using a combination of two-dimensional gradient enhanced HMQC, HMBC experiments and one-dimensional NOE di †erence