Complementary Peptides as Antibody Mimetics for Protein Purification and Assay
β Scribed by Giorgio Fassina
- Book ID
- 115618391
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 770 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1058-6687
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The tetrapeptide GPRP was previously shown to be an effective affinity ligand for fibrinogen when immobilized to Fractogel (Kuyas et aL, 1990). The authors synthesized the GPRP peptide directly onto an aminefunctionalized POROS@ chromatographic resin to demonstrate the effectiveness of this approach
Paratope-specific purification of antibodies has distinct advantages over conventional methods of antibody purification with respect to its capacity to isolate product of high purity and immunoreactivity. The present report addresses the problems of identifying peptide ligands for the purification o