We investigated the IgG subclass reactivity pattern to early antigens (EA) of human cytomegalovirus (HCMV) in 217 EA-antibody-positive sera from immunocompetent, healthy persons, renal transplant recipients and AIDS patients by immunoblotting. All IgG subclasses are involved in the IgG immune respon
✦ LIBER ✦
Complement-fixing antibodies to human cytomegalovirus induced early nuclear antigens in mononucleosis
✍ Scribed by L. Gergely; Judith Czeglédy; L. Váczi
- Publisher
- Springer-Verlag
- Year
- 1981
- Tongue
- English
- Weight
- 450 KB
- Volume
- 170
- Category
- Article
- ISSN
- 0300-8584
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A human monoclonal antibody to cytomegalovirus (CMV) was produced by transforming peripheral blood mononuclear cells of a patient with recent CMV infection. It is directed against a late antigen located in the nucleus of CMV infected fibroblasts at 24-72 hours postinfection and immuneprecipitates 65