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Complement factor B in retinal pigment epithelial cell is up-regulated by inflammatory cytokine TNF-α and INF-γ

✍ Scribed by Mei Chen; Marie Robertson; John Forrester; Heping Xu


Book ID
116756516
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
55 KB
Volume
44
Category
Article
ISSN
0161-5890

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## Abstract One of the earliest signs of age‐related macular degeneration (AMD) is the formation of drusen which are extracellular deposits beneath the retinal pigmented epithelium (RPE). To investigate the relationship between drusen and AMD, we focused on amyloid β (Aβ), a major component of drus