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Competition between protein aggregation and protein complex formation

โœ Scribed by Sebastian Pechmann; Emmanuel D Levy; Gian G Tartaglia; Michele Vendruscolo

Book ID
115001597
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
303 KB
Volume
9
Category
Article
ISSN
1471-2105

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Protein aggregation has been associated with a number of human diseases, and is a serious problem in the manufacture of recombinant proteins. Of particular interest to the biotechnology industry is deleterious aggregation that occurs during the refolding of proteins from inclusion bodies. As a compl