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Competition between folding and aggregation in a model for protein solutions

✍ Scribed by M. Maiti; M. Rao; S. Sastry

Book ID
111632593
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
540 KB
Volume
32
Category
Article
ISSN
1292-8941

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Protein aggregation has been associated with a number of human diseases, and is a serious problem in the manufacture of recombinant proteins. Of particular interest to the biotechnology industry is deleterious aggregation that occurs during the refolding of proteins from inclusion bodies. As a compl