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Competing Presynaptic and Postsynaptic Effects of Ethanol on Cerebellar Purkinje Neurons

✍ Scribed by Zhen Ming; Hugh E. Criswell; Guozhong Yu; George R. Breese

Book ID
109123561
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
229 KB
Volume
30
Category
Article
ISSN
0145-6008

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Acute administration of alprazolam causes a dose-dependent slowing of the spontaneous discharge of cerebellar Purkinje neurons. This effect is reversed by treatment with propran-0101. There is also significantly less slowing in animals in which cerebellar neuronal circuitry has been destroyed by pre