✦ LIBER ✦

Effects of alprazolam on the activity of rat cerebellar purkinje neurons: Evidence for mediation by norepinephrine

✍ Scribed by Stephen Sorensen; Dr. Robert Freedman

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 430 KB
Volume: 3
Category: Article
ISSN: 0272-4391
DOI: 10.1002/ddr.430030607

No coin nor oath required. For personal study only.

✦ Synopsis

Acute administration of alprazolam causes a dose-dependent slowing of the spontaneous discharge of cerebellar Purkinje neurons. This effect is reversed by treatment with propran-0101. There is also significantly less slowing in animals in which cerebellar neuronal circuitry has been destroyed by pretreatment with 6-hydroxydopamine. These data suggest that some of the depressant effects of alpratofam may be mediated by an interaction with norepinephrine.

📜 SIMILAR VOLUMES

Distinct electrophysiological effects of

Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons

✍ Eliyahu Dremencov; Mostafa El Mansari; Pierre Blier 📂 Article 📅 2007 🏛 Springer 🌐 English ⚖ 232 KB

Excitatory responses to serotonin (5-HT)

Excitatory responses to serotonin (5-HT) in neurons of the rat piriform cortex: Evidence for mediation by 5-HT1C receptors in pyramidal cells and 5-HT2 receptors in interneurons

✍ Priscilla W. Sheldon; George K. Aghajanian 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 1015 KB

As a prerequisite to pharmacological analysis of the excitatory effects of serotonin (5-HT) on piriform pyramidal cells and interneurons, this study first examined the physiological characteristics of these two cell types. Intracellular recordings confirmed that the subpopulation of 5-HT-activated c

The actions of ryanodine on Ca2+-activat

The actions of ryanodine on Ca2+-activated conductances in rat cultured DRG neurones; evidence for Ca2+-induced Ca2+ release

✍ A. Ayar; R. H. Scott 📂 Article 📅 1999 🏛 Springer-Verlag 🌐 English ⚖ 129 KB

The effect of hexamethonium on the diste

The effect of hexamethonium on the distension-induced contractile activity of the rat bladder: Evidence for the existence of a spinal ‘short-loop’ vesicovestioal reflex in rats

✍ Carlo Alberto Maggi; Paolo Santicioli; Alberto Meli 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 509 KB

Effects of temperature on the degradatio

Effects of temperature on the degradation and biliary secretion of asialoorosomucoid by the perfused rat liver: Evidence for two intracellular pathways

✍ Thomas M. Kloppel 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 690 KB

Absence of evidence for a powerful tonic

Absence of evidence for a powerful tonic baroreflex-mediated inhibition on catechol activity in the rat rostral ventrolateral medulla: in vivo voltammetric evidence during sino-aortic deafferentation

✍ N. Rentero; N. Bruandet; L. Quintin 📂 Article 📅 1997 🏛 Springer 🌐 English ⚖ 911 KB