Cycloaddition Reactions of ฮฑ-Lactams wit
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Gerrit L'abbรฉ; Alex Van Asch; Suzanne Toppet
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Article
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2010
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Wiley (John Wiley & Sons)
โ 95 KB
In an excellent review' Lengyel and Sheehan have discussed the chemistry of alactams and pointed out that they appear to be unreactive as 1,3-dipoles in cycloaddition reactions. However, a-lactams possess a more than reasonable tendency to undergo ring opening by cleavage of the (sp3)C-N bond' in or