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Compensatory Increases in Her-2/neu Activation in Response to EGFR Tyrosine Kinase Inhibition in Colon Cancer Cell Lines

โœ Scribed by Peter A. Learn; Naveen Krishnegowda; Jose Talamantez; Morton S. Kahlenberg


Book ID
116702740
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
519 KB
Volume
136
Category
Article
ISSN
0022-4804

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## Abstract Herโ€2/__neu__ overexpression in human breast cancer leads to an aggressive biological behavior and poor prognosis. Although the antiโ€Herโ€2/__neu__ antibody trastuzumab (Herceptinยฎ) has become a valuable therapeutic option for patients with Herโ€2/__neu__โ€overexpressing breast cancer, man