This study examines slice selection and diffusion as sources of systematic error in Tz estimates obtained from imaging experiments. The selective refocusing pulses in a multislice, two-echo, spin-warp experiment cause slice profiles of sequential echoes to change in shape. This results in bias in T2
Compensation of Diffusion Effects in T2 Measurements
✍ Scribed by Ralf Deichmann; Holger Adolf; Erwin Kuchenbrod; Ulrike Nöth; Christian Schwarzbauer; Axel Haase
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 276 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Measurements of the transverse relaxation time T~2~ are usually conducted with the Carr Purcell Meiboom Gill (CPMG) pulse sequence, which causes T~2~‐weighted magnetization. Diffusion effects are a common source of error in measurements of this kind, because the incoherent motion of spins in external magnetic field gradients distorts T~2~ weighting of the transverse magnetization. As a result, inaccurate T~2~‐values are obtained. In this work, we present a method which completely compensates for the effect of diffusion.
📜 SIMILAR VOLUMES
## Abstract It has recently been demonstrated that magnetic resonance (MR) imaging of human lungs and airways is possible with hyperpolarized gases such as ^3^He. Because the influence of the apparent transversal relaxation (__T__~2~\* decay) and diffusion in ^3^He imaging have not been quantified,
The effects of using spatially selective and nonuniform radiofrequency pulses on the apparent T2 of a train of multiple echoes have been calculated by computer simulation. It is demonstrated that the use of selective pulses produces errors in estimates of T2 in imaging experiments because regions of
Quantitative, vascular T2 measurements are of interest for applications such as MR oximetry. In the situation of a vessel with long T2 relaxation times embedded in tissue with relatively short T2 values, contamination of the blood signal from the surrounding tissue can bias T2 measurements. Limited