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Compartmentalization of class II antigen presentation: contribution of cytoplasmic and endosomal processing

✍ Scribed by Ping Li; Josetta L. Gregg; Nan Wang; Delu Zhou; Patrick O'Donnell; Janice S. Blum; Victoria L. Crotzer

Book ID
110746619
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
708 KB
Volume
207
Category
Article
ISSN
0105-2896

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## Abstract The MHC class II‐associated invariant chain (Ii) has several important functions in antigen presentation. In this study, we have examined the effect of Iip33 expression on endocytic transport and antigen presentation. We find that degradation of both endocytosed antigen and Ii itself is