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Comparison of Viral replication fitness of wild-type and lamivudine-resistant HBV in patients

โœ Scribed by Iv, William Delaney; Westland, Christopher; Yang, Huiling; Namini, Hamid; Thibault, Vincent; Benhamou, Yves; Brosgart, Carol; Gibbs, Craig; Miller, Michael; Xiong, Shelly


Book ID
123181340
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
252 KB
Volume
124
Category
Article
ISSN
0016-5085

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The addition of adefovir dipivoxil (ADV) to ongoing lamivudine therapy is effective against lamivudine-resistant virus in patients with hepatitis B virus (HBV) infection. We studied 39 patients who received ADV added to lamivudine for breakthrough hepatitis. We determined early viral changes (12 wee