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Comparison of viral replication fitness of wild-type and lamivudine-resistant HBV in patients

โœ Scribed by W.E. Delaney IV; C. Westland; H. Yang; H. Namini; V. Thibault; Y. Benhamou; J. Fry; C. Brosgart; C. Gibbs; M. Miller; S. Xiong


Book ID
118566008
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
319 KB
Volume
38
Category
Article
ISSN
0168-8278

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The addition of adefovir dipivoxil (ADV) to ongoing lamivudine therapy is effective against lamivudine-resistant virus in patients with hepatitis B virus (HBV) infection. We studied 39 patients who received ADV added to lamivudine for breakthrough hepatitis. We determined early viral changes (12 wee