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Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

✍ Scribed by Ristimäki, Ari; Kumar, Vijay; Gunji, Yuji; Klefstrom, Juha; Kivinen, Laura; Laiho, Marikki; Olofsson, Birgitta; Joukov, Vladimir; Enholm, Berndt; Paavonen, Karri

Book ID: 110060706
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 601 KB
Volume: 14
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1201090

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## Abstract ## BACKGROUND Previous reports indicate that Genistein, a naturally occurring isoflavonoid, exhibits strong antiangiogenic activity. The underlying mechanism of inhibition, however, remains unclear. Among the biologic effects of Genistein are the inhibition of tyrosine kinases and the