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Comparison of total oral bioavailability and the lymphatic transport of halofantrine from three different unsaturated triglycerides in lymph-cannulated conscious rats

✍ Scribed by René Holm; Anette Müllertz; Egon Christensen; Carl-Erik Høy; Henning G Kristensen


Book ID
114301936
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
131 KB
Volume
14
Category
Article
ISSN
0928-0987

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The contribution of lymphatic transport and absorption directly into the portal blood to the overall oral bioavailability of a model lipophilic drug, halofantrine (Hf), was determined in lymph-cannulated, conscious, unrestrained rats after administration in lipidic vehicles with different fatty acid