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Comparison of three assays for the detection of GAD65Ab-specific anti-idiotypic antibodies

✍ Scribed by Shilpa Oak; Jared Radtke; Mona Landin-Olsson; Carina Törn; Ake Lernmark; Christiane S. Hampe

Book ID
113717735
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
455 KB
Volume
351
Category
Article
ISSN
0022-1759

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The administration of xenogenic monoclonal antibodies (MAbs) leads in many cases to a host immune response represented by the generation of antibodies that can be directed against allotypic, isotypic, and idiotypic determinants present on the xenogeneic MAb. Anti-idiotypic antibodies (Ab2s) can be d