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Isolation of human anti-idiotypic antibodies by phage display for clinical immune response assays

✍ Scribed by M. Tornetta; D. Fisher; K. O'Neil; D. Geng; A. Schantz; M. Brigham-Burke; D. Lombardo; D. Fink; D. Knight; R. Sweet; P. Tsui


Book ID
113717436
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
403 KB
Volume
328
Category
Article
ISSN
0022-1759

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## Abstract Human CD48, a membrane‐bound, glycosylphosphatidylinositol (GPI)‐linked glycoprotein, is a potential tumour target for the treatment of leukaemias and lymphomas. CD48 is expressed on T‐ and B‐cells, however <5% of CD34^+^ progenitor cells express CD48. A truncated, 45 kDa soluble form o