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Comparison of three amino acid analysis methods and their application to the amino acid impurity analysis for the development of high-purity amino acid certified reference materials

✍ Scribed by Kato, Megumi; Yamazaki, Taichi; Goto, Mari; Yoshioka, Mariko; Kato, Hisashi; Takatsu, Akiko


Book ID
121597186
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
370 KB
Volume
18
Category
Article
ISSN
0949-1775

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✍ Ulrike Holzgrabe; Cees-Jan Nap; Tanja Beyer; Stefan Almeling πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 305 KB

## Abstract The quality control of drugs is important for safety of patients and consumers. International pharmacopoeias mostly employed HPLC with UV detection for this purpose. This is always a problem when the drugs, such as most amino acids, are lacking a chromophor. Instead of UV detection, the