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Comparison of the “specific” binding of [3H]GABA and [3H]muscimol to a particulate fraction of rat brain

✍ Scribed by DeFeudis, Francis V.; Ossola, Lucienne; Mandel, Paul


Book ID
122977384
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
391 KB
Volume
10
Category
Article
ISSN
0306-3623

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Autoradiographic localization of3H-GABA
✍ E. Hösli; L. Hösli 📂 Article 📅 1980 🏛 Springer-Verlag 🌐 English ⚖ 703 KB

Autoradiographic studies were conducted on the binding of 3H-GABA and 3H-muscimol in cultures of rat cerebellum. Binding sites for both substances were observed on many cerebellar neurones, such as Purkinje cells and interneurones, but not on glial cells. Binding of 3H-GABA and 3H-muscimol was inhib