๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Comparison of the pharmacokinetics of dolasetron and its major active metabolite, reduced dolasetron, in dog

โœ Scribed by J. Dow; G. F. Di Francesco; C. Berg

Book ID
109388546
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
116 KB
Volume
85
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Single- and multiple-dose pharmacokineti
Single- and multiple-dose pharmacokinetics of oral dolasetron and its active metabolites in healthy volunteers: part 2
โœ Dan C. Dimmitt; Youn Sung Choo; Lorene A. Martin; Thangam Arumugham; William F. ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 132 KB ๐Ÿ‘ 2 views

The single-and multiple-dose pharmacokinetics and dose-proportionality of oral dolasetron and its active metabolites over the therapeutic dose range was investigated in 18 healthy men. In an open-label, randomized, complete three-way crossover design, each subject received three separate doses: 50,

Actions of dolasetron and its major meta
Actions of dolasetron and its major metabolite on guinea-pig papillary muscle fibres and the ฮฑ-subunit of human heart sodium channels expressed in Xenopus oocytes
โœ Robert Dumaine; Hali A. Hartmann; Derek J. Leishman; Arthur M. Brown; Martin Gal ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 695 KB

The present study evaluated the effects of the anti-emetic 5-HT3 antagonist dolasetron and its major metabolite MDL 73,405 on guinea-pig papillary muscle fibres and human heart sodium channels expressed in Xenopus oocytes. Dolasetron and MDL 73,405 (3-10 p M ) reduced the maximum depolarization rate