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Comparison of the in vivo and in vitro rates of formation of the three main oxidative metabolites of antipyrine in man.

✍ Scribed by AR Boobis; MJ Brodie; GC Kahn; EL Toverud; IA Blair; S Murray; DS Davies

Book ID
117942662
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
934 KB
Volume
12
Category
Article
ISSN
0306-5251

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A radiometric high-pressure liquid chrom
A radiometric high-pressure liquid chromatography assay for the simultaneous determination of the three main oxidative metabolites of antipyrine in studies in vitro
✍ G. Clare Kahn; Alan R. Boobis; Ian A. Blair; Martin J. Brodie; Donald S. Davies πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 English βš– 663 KB

A quantitative radiometric high-pressure liquid chromatography assay for the estimation of the three main oxidative metabolites of antipyrine in vitro using [3-'\*C]antipyrine as substrate is described. Baseline separation of antipyrine, 3-hydroxymethylantipyrine, 4-hydroxyantipyrine, and norphenazo