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Comparison of the high-resolution structures of the α-amylase inhibitor tendamistat determined by nuclear magnetic resonance in solution and by X-ray diffraction in single crystals

✍ Scribed by Martin Billeter; Allen D. Kline; Werner Braun; Robert Huber; Kurt Wüthrich


Book ID
118918816
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
1018 KB
Volume
206
Category
Article
ISSN
0022-2836

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Restrained energy refinement with two di
✍ M. Billeter; Th. Schaumann; W. Braun; K. Wüthrich 📂 Article 📅 1990 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 982 KB

The solution structure of an a-amylase inhibitor, tendamistat, calculated from nmr data with the distance geometry program DISMAN is subjected to restrained energy minimization. To study the influence of force field parametrizations and the convergence behavior of refinement algorithms, two differen