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Comparison of the electrophoretic and hydrodynamic properties of DNA and RNA oligonucleotide duplexes

✍ Scribed by Bonifacio, G.F.; Brown, T.; Conn, G.L.; Lane, A.N.


Book ID
119411100
Publisher
Biophysical Society
Year
1997
Tongue
English
Weight
726 KB
Volume
73
Category
Article
ISSN
0006-3495

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## Background The high binding specificity of short 10 to 30 mer oligonucleotide probes enables single base mismatch (MM) discrimination and thus provides the basis for genotyping and resequencing microarray applications. Recent experiments indicate that the underlying principles governing DNA micr