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Comparison of the DNA methylation profiles of human peripheral blood cells and transformed B-lymphocytes

โœ Scribed by Yan V. Sun; Stephen T. Turner; Jennifer A. Smith; Pamela I. Hammond; Alicia Lazarus; Jodie L. Van De Rostyne; Julie M. Cunningham; Sharon L. R. Kardia

Book ID
106134974
Publisher
Springer
Year
2010
Tongue
English
Weight
413 KB
Volume
127
Category
Article
ISSN
0340-6717

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In this study we have evaluated the genoprotective effect of the ethanol extract of Gymnema montanum (GLEt) leaves in human peripheral blood lymphocytes and HL-60 cell line in vitro using the comet assay. DNA damage was induced by treating the cells with H 2 O 2 and methyl methane sulphonate (MMS).